Article
Amino acid residue 67 (isoleucine) of HLA-DRB is associated with POHS.
Investigative ophthalmology & visual science - 1 Jun 2002
Ongkosuwito Jenny V, Tilanus Marcel G J, Van der Lelij Allegonda, van Schooneveld Mary J, Jager Martine J, Rozemuller Erik H, de Smet Marc D, Suttorp-Schulten Maria S A
Abstract excerpt
PURPOSE: To investigate whether presumed ocular histoplasmosis syndrome (POHS) in The Netherlands is associated with HLA-DR2 and HLA-B7, as previously shown in the United States. METHODS: Twenty-four Dutch patients with POHS were included in this study. DNA isolated from peripheral blood leukocytes was typed for HLA by a sequence-based method. Associations were statistically determined. The frequencies of HLA...
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