Article
A new HLA extended haplotype containing the A*2910 allele in birdshot retinochoroidopathy: susceptibility narrowed to the HLA molecule itself.
Investigative ophthalmology & visual science - 1 May 2010
Donvito Béatrice, Monnet Dominique, Tabary Thierry, Delair Emmanuelle, Vittier Mélanie, Réveil Brigitte, Chiquet Christophe, Brézin Antoine P, Cohen Jacques H M
Abstract excerpt
PURPOSE: Birdshot retinochoroidopathy (BSRC) is a rare posterior uveitis characterized by distinctive, multiple, hypopigmented choroidal and retinal lesions. Most, if not all, patients are white and share the major histocompatibility antigen HLA-A29. Furthermore, the A*2902 subtype is closely associated with BSRC, and only a very few patients share the A*2901 subtype. Surprisingly, although A*2901 and A*2902...
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