Article
Phenotypic and genotypic variation in methylases involved in type II restriction-modification systems in Helicobacter pylori.
Nucleic acids research - 1 Jun 2002
Takata Tohru, Aras Rahul, Tavakoli Donald, Ando Takafumi, Olivares Asalia Z, Blaser Martin J
Abstract excerpt
To determine relationships between Helicobacter pylori geographical origin and type II methylase activity, we examined 122 strains from various locations around the world for methylase expression. Most geographic regions possessed at least one strain resistant to digestion by each of 14 restriction endonucleases studied. Across all of the strains studied, the average number of active methylases was 8.2 +/- 1.9...
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