Article
Genetic diversity of the HpyC1I restriction modification system in Helicobacter pylori.
Research in microbiology - 1 Apr 2007
Lehours Philippe, Dupouy Sandrine, Chaineux Julien, Ruskoné-Fourmestraux Agnès, Delchier Jean-Charles, Morgner Andrea, Mégraud Francis, Ménard Armelle
Abstract excerpt
Helicobacter pylori is unique because of the unusually high number and diversity of its restriction modification (R-M) systems. HpyC1I R-M was recently characterized and contains an endonuclease which is an isoschizomer of the endonuclease BccI. This R-M is involved in adherence to gastric epithelial cells, a crucial step in bacterial pathogenesis. This observation illustrates the fact that R-M systems have other...
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