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Article

Identification of type II restriction and modification systems in Helicobacter pylori reveals their substantial diversity among strains.

Proceedings of the National Academy of Sciences of the United States of America - 15 Aug 2000

Xu Q, Morgan R D, Roberts R J, Blaser M J

Abstract excerpt

A total of 22 type II restriction endonucleases with 18 distinct specificities have been identified in six Helicobacter pylori strains. Among these 18 specificities are three completely new endonucleases, Hpy178III, Hpy99I, and Hpy188I, that specifically cleave DNA at TCNNGA, CGWCG, and TCNGA sites, respectively. The set of endonucleases identified in each strain varies, but all have four- or five-base...

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Share to Chromosomes, Bacterial
Share to Deoxyribonucleases, Type II Site-Specific

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10944229
DOI: 10.1073/pnas.97.17.9671
PMCID: PMC16923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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