Article
Population Evolution of Helicobacter pylori through Diversification in DNA Methylation and Interstrain Sequence Homogenization.
Molecular biology and evolution - 1 Nov 2016
Kojima Kenji K, Furuta Yoshikazu, Yahara Koji, Fukuyo Masaki, Shiwa Yuh, Nishiumi Shin, Yoshida Masaru, Azuma Takeshi, Yoshikawa Hirofumi, Kobayashi Ichizo
Abstract excerpt
Decoding of closely related genomes is now revealing the process of population evolution. In bacteria, population divergence appears associated with a unique set of sequence-specific epigenetic DNA methylation systems, often within restriction-modification (RM) systems. They might define a unique gene expression pattern and limit genetic flux between lineages in population divergence. We addressed the...
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