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Article

Genome and Methylome Variation in Helicobacter pylori With a cag Pathogenicity Island During Early Stages of Human Infection.

Gastroenterology - 1 Feb 2018

Nell Sandra, Estibariz Iratxe, Krebes Juliane, Bunk Boyke, Graham David Y, Overmann Jörg, Song Yi, Spröer Cathrin, Yang Ines, Wex Thomas, Korlach Jonas, Malfertheiner Peter, Suerbaum Sebastian

Abstract excerpt

BACKGROUND & AIMS: Helicobacter pylori is remarkable for its genetic variation; yet, little is known about its genetic changes during early stages of human infection, as the bacteria adapt to their new environment. We analyzed genome and methylome variations in a fully virulent strain of H pylori during experimental infection. METHODS: We performed a randomized Phase I/II, observer-blind, placebo-controlled study...

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PMID: 29066327
DOI: 10.1053/j.gastro.2017.10.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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