Article
HIV drug resistance and implications for the introduction of antiretroviral therapy in resource-poor countries.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy - 1 Dec 2001
Petrella M, Brenner B, Loemba H, Wainberg M A
Abstract excerpt
The development and transmission of HIV drug-resistant viruses is of serious concern and has been shown to significantly diminish the effectiveness of antiretroviral therapy. In addition, cross-resistance between drugs of the same class can seriously limit therapeutic options and may potentially be most problematic in resource-poor settings where new drugs are not widely available. Strategies based on avoidance...
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