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Article

Genotype and phenotype resistance: an overview.

Journal of biological regulators and homeostatic agents - 1 Jan 2000

Angarano G, Monno L

Abstract excerpt

Drug resistance is a major factor contributing to the failure of antiretroviral therapy. The rapid turnover of the human immunodeficiency virus type 1 (HIV-1) and the error-prone reverse transcriptase both contribute to the extensive emergence of resistant variants. The understanding of resistance and cross-resistance patterns is essential for the appropriate selection of treatment regimens for HIV-infected...

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PMID: 10763885

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