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Article

Effect of enamel matrix derivative on the differentiation of C2C12 cells.

Journal of periodontology - 1 May 2002

Ohyama Mariko, Suzuki Naoto, Yamaguchi Yoko, Maeno Masao, Otsuka Kichibee, Ito Koichi

Abstract excerpt

BACKGROUND: Although enamel matrix derivative (EMD) can initiate de novo cementum and bone formation by stimulating and inducing differentiation of mesenchymal cells in the periodontal ligament, the molecular mechanism of this phenomenon is not fully understood. The purpose of this study was to determine the effect of EMD on the differentiation of pluripotential mesenchymal cells. METHODS: A typical...

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Source

Identifiers

PMID: 12027258
DOI: 10.1902/jop.2002.73.5.543

Genes

EMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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