Article
Multilineage differentiation of dental follicle cells and the roles of Runx2 over-expression in enhancing osteoblast/cementoblast-related gene expression in dental follicle cells.
Cell proliferation - 1 Jun 2010
Pan K, Sun Q, Zhang J, Ge S, Li S, Zhao Y, Yang P
Abstract excerpt
OBJECTIVES: Dental follicle cells (DFCs) provide the origin of periodontal tissues, and Runx2 is essential for bone formation and tooth development. In this study, pluripotency of DFCs was evaluated and effects of Runx2 on them were investigated. MATERIALS AND METHODS: The DFCs were induced to differentiate towards osteoblasts, adipocytes or chondrocytes, and alizarin red staining, oil red O staining or alcian...
Topics
- Adipocytes
- Animals
- Animals, Newborn
- Cell Differentiation
- Cell Lineage
- Chondrocytes
- Core Binding Factor Alpha 1 Subunit
- Dental Cementum
- Dental Sac
- Gene Expression Regulation, Developmental