Article
The effects of enamel matrix derivative (EMD) on osteoblastic cells in culture and bone regeneration in a rat skull defect.
Journal of periodontal research - 1 Jun 2003
Yoneda Satoshi, Itoh Daisuke, Kuroda Shinji, Kondo Hisatomo, Umezawa Akihiro, Ohya Keiichi, Ohyama Takashi, Kasugai Shohei
Abstract excerpt
OBJECTIVE: Enamel matrix derivative (EMD) has been clinically used to promote periodontal tissue regeneration. The purpose of the present study is to clarify EMD affects on osteoblastic cells and bone regeneration. MATERIALS AND METHODS: Mouse osteoblastic cells (ST2 cells and KUSA/A1 cells) are used in culture experiments. After cells were treated with EMD, cell growth was evaluated with DNA measurement,...
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