Article
MIC-A genotypes 4/5.1 and 9/9 are positively associated with type 1 diabetes mellitus in Brazilian population.
Annals of the New York Academy of Sciences - 1 Nov 2003
Tica Valeria, Nikitina-Zake Liene, Donadi Eduardo, Sanjeevi Carani B
Abstract excerpt
The aim of our study was to evaluate the frequencies of MIC-A alleles and genotypes in Brazilian patients with type 1 diabetes mellitus (T1DM) and healthy controls. MHC class I chain-related gene-A (MIC-A) has been shown to be associated with susceptibility to T1DM in different populations. We analyzed the DNA samples from 86 patients and 201 healthy controls for MIC-A by PCR amplification, and fragment sizes...
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