Article
Coordinated transcription of key pathways in the mouse by the circadian clock.
Cell - 3 May 2002
Panda Satchidananda, Antoch Marina P, Miller Brooke H, Su Andrew I, Schook Andrew B, Straume Marty, Schultz Peter G, Kay Steve A, Takahashi Joseph S, Hogenesch John B
Abstract excerpt
In mammals, circadian control of physiology and behavior is driven by a master pacemaker located in the suprachiasmatic nuclei (SCN) of the hypothalamus. We have used gene expression profiling to identify cycling transcripts in the SCN and in the liver. Our analysis revealed approximately 650 cycling transcripts and showed that the majority of these were specific to either the SCN or the liver. Genetic and...
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