Article
A common mechanism of action for three mood-stabilizing drugs.
Nature - 16 May 2002
Williams Robin S B, Cheng Lili, Mudge Anne W, Harwood Adrian J
Abstract excerpt
Lithium, carbamazepine and valproic acid are effective mood-stabilizing treatments for bipolar affective disorder. The molecular mechanisms underlying the actions of these drugs and the illness itself are unknown. Berridge and colleagues suggested that inositol depletion may be the way that lithi...
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