Iron reduction and sustained response to interferon-alpha therapy in patients with chronic hepatitis C: results of an Italian multicenter randomized study.

doi:10.1111/j.1572-0241.2002.05705.x

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Article

Iron reduction and sustained response to interferon-alpha therapy in patients with chronic hepatitis C: results of an Italian multicenter randomized study.

The American journal of gastroenterology - 1 May 2002

Fargion Silvia, Fracanzani Anna Ludovica, Rossini Angelo, Borzio Mauro, Riggio Oliviero, Belloni Giovanni, Bissoli Franco, Ceriani Roberto, Ballarè Marco, Massari Marco, Trischitta Caterina, Fiore Pierluigi, Orlandi Anna, Morini Lorenzo, Mattioli Michela, Oldani Silvia, Cesana Bruno, Fiorelli Gemino

Abstract excerpt

OBJECTIVES: It has been suggested that iron depletion improves the response to interferon in patients with chronic hepatitis C. We aimed to evaluate whether iron reduction by phlebotomy before interferon improves the rate of virological sustained response in previously untreated noncirrhotic patients. METHODS: One hundred fourteen hepatitis C virus (HCV) RNA positive patients with hepatic iron concentrations of >...

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PMID: 12014729
DOI: 10.1111/j.1572-0241.2002.05705.x

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