Article
Resistance to p53-mediated growth suppression in human ovarian cancer cells retain endogenous wild-type p53.
Anticancer research - 1 Jan 2000
Jin X, Burke W, Rothman K, Lin J
Abstract excerpt
Cancer cells containing mutated p53 are sensitive to the re-introduction of the wild-type (wt) p53. We sought to determine whether ovarian cancer cells that retain wt p53 are sensitive to the re-introduction of wt p53. Our results demonstrated that A2780 and PA-1 cells, which retain wt p53, are m...
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