Article
Transcriptional and mutational analysis of the Helicobacter pylori urease promoter.
FEMS microbiology letters - 16 Jul 2002
Davies Beverly J, de Vries Nicolette, Rijpkema Sjoerd G, van Vliet Arnoud H M, Penn Charles W
Abstract excerpt
Urease is an essential virulence factor of the human gastric pathogen Helicobacter pylori, and is expressed to very high levels. The promoter of the urease operon contains sequences resembling the canonical -10 and extended -10 motifs, but no discernible -35 motif. To establish the role of different motifs and regions in the urease promoter, we fused the urease promoter to a genomic lacZ reporter gene in H....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.