Article
No association of plasma prothrombin concentration or the G20210A mutation with incident cardiovascular disease: results from the Cardiovascular Health Study.
Thrombosis and haemostasis - 1 Apr 2002
Smiles Adam M, Jenny Nancy S, Tang Zhonghua, Arnold Alice, Cushman Mary, Tracy Russell P
Abstract excerpt
Prothrombin is a key factor in blood clotting, a process intimately involved in thrombotic disease. We assessed prothrombin levels and G20210A genotype in a case-control study within the Cardiovascular Health Study. Cases included angina, myocardial infarction, stroke, and the presence of MRI-detectable infarcts (n approximately 250 each). Population-based controls free of clinical cardiovascular disease (CVD) (n...
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