Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lysyl Oxidase Activity Is Dysregulated during Impaired Alveolarization of Mouse and Human Lungs

25 Sept 2009

Abstract excerpt

RATIONALE: Disordered extracellular matrix production is a feature of bronchopulmonary dysplasia (BPD). The basis of this phenomenon is not understood. OBJECTIVES: To assess lysyl oxidase expression and activity in the injured developing lungs of newborn mice and of prematurely born infants with BPD or at risk for BPD. METHODS: Pulmonary lysyl oxidase and elastin gene and protein expression were assessed in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connective tissue disorders research
Share to Microbial metabolism and enzyme function
Share to Neonatal Respiratory Health Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19797161
DOI: 10.1164/rccm.200902-0215oc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lysyl Oxidase Activity Is Dysregulated during Impaired Alveolarization of Mouse and Human LungsPMID 19797161Read ↗

Deregulation of the lysyl hydroxylase matrix cross-linking system in experimental and clinical bronchopulmonary dysplasiaSemantic proximity Read ↗

Lysyl oxidase is required for vascular and diaphragmatic development in mice.Semantic proximity Read ↗

Comparative analysis of lysyl oxidase (like) family members in pulmonary fibrosisSemantic proximity Read ↗

Neonatal periostin knockout mice are protected from hyperoxia-induced alveolar simplication.Semantic proximity Read ↗

Significance of nuclear upregulation of LOXL2 in fibroblasts and myofibroblasts in the fibrotic process of acute respiratory distress syndromeSemantic proximity Read ↗

Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice.Semantic proximity Read ↗

Sex-Linked Skeletal Phenotype of Lysyl Oxidase Like-1 Mutant Mice.Semantic proximity Read ↗

Differential expression of long non‐coding RNAs in hyperoxia‐induced bronchopulmonary dysplasiaSemantic proximity Read ↗

Mouse lung development and NOX1 induction during hyperoxia are developmentally regulated and mitochondrial ROS dependentSemantic proximity Read ↗

Genome-Wide Transcriptional Profiling Reveals Connective Tissue Mast Cell Accumulation in Bronchopulmonary DysplasiaSemantic proximity Read ↗

HIF1α Is Essential for Normal Intrauterine Differentiation of Alveolar Epithelium and Surfactant Production in the Newborn Lung of MiceSemantic proximity Read ↗

Functional importance of lysyl oxidase family propeptide regionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.