Article
The IgA nephropathy Biobank. An important starting point for the genetic dissection of a complex trait.
BMC nephrology - 5 Dec 2005
Schena Francesco P, Cerullo Giuseppina, Torres Diletta D, Scolari Francesco, Foramitti Marina, Amoroso Antonio, Pirulli Doroti, Floege Jürgen, Mertens Peter R, Zerres Klaus, Alexopoulos Efstathios, Kirmizis Dimitrios, Zelante Leopoldo, Bisceglia Luigi, Ghiggeri Gian M, Frascà Giovanni M
Abstract excerpt
BACKGROUND: IgA nephropathy (IgAN) or Berger's disease, is the most common glomerulonephritis in the world diagnosed in renal biopsied patients. The involvement of genetic factors in the pathogenesis of the IgAN is evidenced by ethnic and geographic variations in prevalence, familial clustering in isolated populations, familial aggregation and by the identification of a genetic linkage to locus IGAN1 mapped on...
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