Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV in Africa (Communication arising): chemokine-receptor genes and AIDS risk.

Nature - 9 May 2002

Ramaley Patricia A, French Neil, Kaleebu Pontiano, Gilks Charles, Whitworth James, Hill Adrian V S

Abstract excerpt

Schliekelman et al. have provided a model to quantify the speed at which HIV-resistance haplotypes can become enriched in a susceptible population through a delay in the onset of AIDS, permitting greater lifetime reproduction and the selection of AIDS-delaying haplotypes. But we question their conclusion that there could be a rapid evolution of resistance to AIDS onset in some African populations if the current...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acquired Immunodeficiency Syndrome
Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black People

Share to Receptors, CCR2

Share to Receptors, CCR5

Share to Receptors, Chemokine

Share to Regression Analysis

Share to Uganda

Source

Identifiers

PMID: 12000952
DOI: 10.1038/417140a

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV in Africa (Communication arising): chemokine-receptor genes and AIDS risk.PMID 12000952Read ↗

Common human genetic variants and HIV-1 susceptibility: a genome-wide survey in a homogeneous African population.Semantic proximity Read ↗

[Hypothesis for the formation of human unresponsiveness to immunodeficiency virus].Semantic proximity Read ↗

[HIV-1 chemokine receptors and their role in the pathogenesis of AIDS].Semantic proximity Read ↗

Genetic acceleration of AIDS progression by a promoter variant of CCR5.Semantic proximity Read ↗

Immune activation in Africa is environmentally-driven and is associated with upregulation of CCR5Semantic proximity Read ↗

CCR5 mutations and HIV susceptibility.Semantic proximity Read ↗

Disparate associations of HLA class I markers with HIV-1 acquisition and control of viremia in an African population.Semantic proximity Read ↗

Potential role of CCR5 polymorphism in the development of AIDS dementia complex.Semantic proximity Read ↗

Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians.Semantic proximity Read ↗

Influence of CCR5 promoter haplotypes on AIDS progression in African-Americans.Semantic proximity Read ↗

Concordance between the CC chemokine receptor 5 genetic determinants that alter risks of transmission and disease progression in children exposed perinatally to human immunodeficiency virus.Semantic proximity Read ↗

Regulation of CCR5 expression in human placenta: insights from a study of mother-to-child transmission of HIV in Malawi.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.