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Article

Immune activation in Africa is environmentally-driven and is associated with upregulation of CCR5

1 Sept 2000

Abstract excerpt

BACKGROUND: HIV infection in Africa is associated with immune activation and a cytokine profile that stimulates CCR5 expression. We investigated whether this immune activation is environmentally driven; if a dominant expression of CCR5 could indeed be detected in African individuals; and if R5 HIV strains would be prevalent in this population. METHODS: Freshly drawn peripheral blood mononuclear cells from...

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PMID: 11061648
DOI: 10.1097/00002030-200009290-00003

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