Article
Neutral sphingomyelinase 1 deficiency in the mouse causes no lipid storage disease.
Molecular and cellular biology - 1 Jun 2002
Zumbansen Markus, Stoffel Wilhelm
Abstract excerpt
Sphingomyelin is a major lipid in the bilayer of subcellular membranes of eukaryotic cells. Different sphingomyelinases catalyze the initial step in the catabolism of sphingomyelin, the hydrolysis to phosphocholine and ceramide. Sphingomyelinases have been postulated to generate ceramide as a lip...
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