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Article

Neutral sphingomyelinase 2 (smpd3) in the control of postnatal growth and development.

Proceedings of the National Academy of Sciences of the United States of America - 22 Mar 2005

Stoffel Wilhelm, Jenke Britta, Blöck Barbara, Zumbansen Markus, Koebke Jürgen

Abstract excerpt

Neutral sphingomyelinases sphingomyelin phosphodiesterase (SMPD)2 and -3 hydrolyze sphingomyelin to phosphocholine and ceramide. smpd2 is expressed ubiquitously, and smpd3 is expressed predominantly in neurons of the CNS. Their activation and the functions of the released ceramides have been asso...

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Identifiers

PMID: 15764706
DOI: 10.1073/pnas.0406380102
PMCID: PMC555473

Genes

SMPD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15764706-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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