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Article

The human alphaE-catenin gene CTNNA1: mutational analysis and rare occurrence of a truncated splice variant.

Biochimica et biophysica acta - 12 Apr 2002

Vanpoucke Griet, Nollet Friedel, Tejpar Sabine, Cassiman Jean-Jacques, van Roy Frans

Abstract excerpt

Abnormal expression of the alphaE-catenin protein, a component of the E-cadherin/catenin cell adhesion complex, is frequently observed in human cancer cells. An inverse correlation between alphaE-catenin expression and tumor malignancy can be of prognostic value. Mutations of the alphaE-catenin gene, CTNNA1, were described in several human cancer cell lines and were found to result in aberrant cell adhesion. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11997091
DOI: 10.1016/s0167-4781(01)00378-5

Genes

CTNNA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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