Article
Genetic contribution to factor VII levels in families of patients undergoing coronary arteriography.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jan 2002
Jee S H, Song K S, Shim W, Kim H K, Suh I, Yoon Y, Beaty T H
Abstract excerpt
An elevated plasma level of factor VII is a risk factor for coronary artery disease. We investigated environmental, familial, and genetic influences on factor VII activity in 508 family members of 87 probands who underwent elective coronary arteriography. Maximum likelihood methods were used to fit several genetic and non-genetic models of inheritance to these data to determine whether an unobserved Mendelian...
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