Article
O-phospho-L-tyrosine protects TP53 wild-type cells against ionizing radiation.
International journal of cancer - 1 Jan 2001
Dittmann K H, Mayer C, Rodemann H P
Abstract excerpt
O-phospho-L-tyrosine (P-Tyr) has been reported previously to inhibit growth of several cancer cell lines at mM concentrations. In the present study, we investigated the effect of this compound on tumor cells and normal cells in combination with radiation exposure. It could be demonstrated for the first time that P-Tyr at microM concentrations protects TP53 wild-type cells against ionizing radiation (SF4 minus BBI...
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