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Article

Qualitative analysis of the expression of Epstein--Barr virus lytic genes in nasopharyngeal carcinoma biopsies

1 Jun 1995

Abstract excerpt

We recently showed that BZLF1, the gene encoding the Epstein-Barr virus (EBV) ZEBRA protein, was expressed in all eight nasopharyngeal carcinoma (NPC) specimens studied. We present here studies on the expression of EBV lytic cycle genes in the same eight NPC biopsies to determine if production of the ZEBRA transactivator could lead to a complete productive cycle. The tumour lesions exhibit a number of different...

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PMID: 7782768
DOI: 10.1099/0022-1317-76-6-1401

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