Mutation accumulation in real branches: fitness assays for genomic deleterious mutation rate and effect in large-statured plants.

Abstract excerpt

The genomic deleterious mutation rate and mean effect are central to the biology and evolution of all species. Large-statured plants, such as trees, are predicted to have high mutation rates due to mitotic mutation and the absence of a sheltered germ line, but their size and generation time has hindered genetic study. We develop and test approaches for estimating deleterious mutation rates and effects from...

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