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Article

Bypassing natural sperm selection during fertilization: the azh mutant offspring experience and the alternative of spermiogenesis in vitro.

Molecular and cellular endocrinology - 22 Feb 2002

Kierszenbaum Abraham L, Tres Laura L

Abstract excerpt

Molecular aspects of spermiogenesis can be studied using mouse mutants and spermatids developed in vitro. The azh/azh mutant is an attractive model system because structural abnormalities in the sperm head and the ectopic position of the manchette are associated with tail bending and looping. Spermatids, developing an axoneme in vitro and capable of cell motility, offer the possibility of the dynamic analysis of...

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PMID: 11988320
DOI: 10.1016/s0303-7207(01)00692-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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