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Article

Expression of recombinant murine pregnancy‐associated plasma protein‐A (PAPP‐A) and a novel variant (PAPP‐Ai) with differential proteolytic activity

1 Apr 2002

Abstract excerpt

Murine pregnancy-associated plasma protein-A (PAPP-A) cDNA encoding a 1545 amino-acid protein has been cloned. We have also identified and cloned cDNA that encodes a novel variant of PAPP-A, PAPP-Ai, carrying a 29-residue highly basic insert. The point of insertion corresponds to a junction between two exons in the human PAPP-A gene. The human intron flanked by these exons does not encode a homologous...

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Genetic Syndromes and Imprinting
Growth Hormone and Insulin-like Growth Factors
Prenatal Screening and Diagnostics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11985604
DOI: 10.1046/j.1432-1033.2002.02883.x

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