Article
Apolipoprotein E genotype does not predict decline in intelligence in healthy older adults.
Neuroscience letters - 10 May 2002
Pendleton Neil, Payton Anthony, van den Boogerd Eelke H, Holland Fiona, Diggle Peter, Rabbitt Patrick M A, Horan Michael A, Worthington Jane, Ollier William E R
Abstract excerpt
There is evidence of a genetic influence on the decline in cognitive performance of older adults, although the mechanisms responsible are unknown. A group of 767 subjects of the Manchester University Age and Cognitive Performance longitudinal study volunteer group, followed up from 1985 to the present, were genotyped for apolipoprotein E (APOE). The data from this were related to cross-sectional and longitudinal...
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