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Article

Defective DNA-mismatch repair: a potential mediator of leukemogenic susceptibility in therapy-related myelodysplasia and leukemia.

Genes, chromosomes & cancer - 1 Jun 2002

Olipitz Werner, Hopfinger Georg, Aguiar Ricardo C T, Gunsilius Eberhard, Girschikofsky Michael, Bodner Claudia, Hiden Karin, Linkesch Werner, Hoefler Gerald, Sill Heinz

Abstract excerpt

We investigated the potential role of defective DNA-mismatch repair (MMR) as a mediator of leukemogenic susceptibility in patients with therapy-related myelodysplasia (t-MDS) and leukemia (t-leuk). Thirty-seven individuals with t-MDS/t-leuk were analyzed for microsatellite instability (MSI), the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11979558
DOI: 10.1002/gcc.10059

Genes

APC
BAX
MBD4
MSH3
MSH6
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11979558-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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