Article
Pharmacogenetics: has it reached the clinic?
The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia - 1 Jan 2000
Schwartz Janice B
Abstract excerpt
Genetic variation in drug-metabolizing enzymes contributes to the variability in drug responses seen in humans. Information in the area is expanding rapidly, and the clinical significance of many of the polymorphisms is only now being elucidated. It is clear that polymorphism frequency varies markedly by race and ethnicity, but major differences by sex have not been reported. Screening for genetic variation in...
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