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Article

Ets-1 positively regulates Fas ligand transcription via cooperative interactions with Sp1.

The Journal of biological chemistry - 27 Sept 2002

Kavurma Mary M, Bobryshev Yuri, Khachigian Levon M

Abstract excerpt

The FasL/Fas system has been implicated in smooth muscle cell apoptosis and atherosclerotic plaque instability, a process that can lead to plaque rupture, precipitating myocardial infarction and sudden death. The transcriptional mechanisms regulating FasL gene expression in vascular smooth muscle cells are poorly understood. We recently described a novel mechanism mediating inducible FasL gene expression in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11970950
DOI: 10.1074/jbc.M200463200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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