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Article

Evolution of porcine reproductive and respiratory syndrome virus during sequential passages in pigs.

Journal of virology - 1 May 2002

Chang C-C, Yoon K-J, Zimmerman J J, Harmon K M, Dixon P M, Dvorak C M T, Murtaugh M P

Abstract excerpt

Porcine reproductive and respiratory syndrome (PRRS) viruses are recognized as possessing a high degree of genetic and antigenic variability. Viral diversity has led to questions regarding the association of virus mutation and persistent infection in the host and has raised concerns vis-à-vis protective immunity, the ability of diagnostic assays to detect novel variants, and the possible emergence of virulent...

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Identifiers

PMID: 11967292
DOI: 10.1128/jvi.76.10.4750-4763.2002
PMCID: PMC136148

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