Article
Quasispecies evolution of the prototypical genotype 1 porcine reproductive and respiratory syndrome virus early during in vivo infection is rapid and tissue specific.
Archives of virology - 1 Aug 2017
Lu Zen H, Wang Xinglong, Wilson Alison D, Dorey-Robinson Daniel L W, Archibald Alan L, Ait-Ali Tahar, Frossard Jean-Pierre
Abstract excerpt
Porcine reproductive and respiratory syndrome virus (PRRSV) is a major infectious threat to the pig industry worldwide. Increasing evidence suggests that microevolution within a quasispecies population can give rise to high sequence heterogeneity in PRRSV; potentially impacting the pathogenicity of the virus. Here, we report on micro-evolutionary events taking place within the viral quasispecies population in...
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