Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Antigenic and Biological Characterization of ORF2-6 Variants at Early Times Following PRRSV Infection.

Viruses - 16 May 2017

Evans Alyssa B, Loyd Hyelee, Dunkelberger Jenelle R, van Tol Sarah, Bolton Marcus J, Dorman Karin S, Dekkers Jack C M, Carpenter Susan

Abstract excerpt

Genetic diversity of porcine reproductive and respiratory syndrome virus (PRRSV) challenges efforts to develop effective and broadly acting vaccines. Although genetic variation in PRRSV has been extensively documented, the effects of this variation on virus phenotype are less well understood. In the present study, PRRSV open reading frame (ORF)2-6 variants predominant during the first six weeks following...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Neutralizing
Share to Antigenic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, Viral

Share to Porcine Reproductive and Respiratory Syndrome

Share to Porcine respiratory and reproductive syndrome virus

Share to Sus scrofa

Share to Virion

Share to Virus Attachment

Source

Open in PubMed Open full text

Identifiers

PMID: 28509878
DOI: 10.3390/v9050113
PMCID: PMC5454425

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Antigenic and Biological Characterization of ORF2-6 Variants at Early Times Following PRRSV Infection.PMID 28509878Read ↗

Genetic diversity in envelope genes of contemporary U.S. porcine reproductive and respiratory syndrome virus strains influences viral antigenicity.Semantic proximity Read ↗

Porcine reproductive and respiratory disease virus: Evolution and recombination yields distinct ORF5 RFLP 1-7-4 viruses with individual pathogenicity.Semantic proximity Read ↗

ORF5 of porcine reproductive and respiratory syndrome virus (PRRSV) is a target of diversifying selection as infection progresses from acute infection to virus rebound.Semantic proximity Read ↗

Chimeric HP-PRRSV2 containing an ORF2-6 consensus sequence induces antibodies with broadly neutralizing activity and confers cross protection against virulent NADC30-like isolateSemantic proximity Read ↗

Evolutionary diversification of type 2 porcine reproductive and respiratory syndrome virus.Semantic proximity Read ↗

Genetic and immunobiological diversities of porcine reproductive and respiratory syndrome genotype I strains.Semantic proximity Read ↗

Heterogeneity of porcine reproductive and respiratory syndrome virus: implications for current vaccine efficacy and future vaccine development.Semantic proximity Read ↗

Genetic diversity of ORF 4-6 of type 1 porcine reproductive and respiratory syndrome virus in naturally infected pigs.Semantic proximity Read ↗

Genetic variation in the PRRS virus.Semantic proximity Read ↗

Effect of genotypic and biotypic differences among PRRS viruses on the serologic assessment of pigs for virus infection.Semantic proximity Read ↗

Evolution of porcine reproductive and respiratory syndrome virus during sequential passages in pigs.Semantic proximity Read ↗

The GP2a 91/97/98 amino acid substitutions play critical roles in determining PRRSV tropism and infectivity but do not affect immune responsesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.