Article
Tumor-associated fibroblasts (part I): Active stromal participants in tumor development and progression?
Histology and histopathology - 1 Apr 2002
Kunz-Schughart L A, Knuechel R
Abstract excerpt
Phenotypic and functional characteristics of tumor associated fibroblasts (TAF) in contrast to normal fibroblasts are reviewed in this first synopsis (part I). Terms as tumor stroma, desmo-plasia, TAF, myofibroblast, and fetal-type fibroblast are defined, and experimental systems to study heterologous cell interactions are presented. While we only start to gather information on the genotype of TAF, a broad range...
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