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Article

Gender and smoking-related risk reduction of periodontal disease with variant myeloperoxidase alleles.

Genes and immunity - 1 Apr 2002

Meisel P, Krause T, Cascorbi I, Schroeder W, Herrmann F, John U, Kocher Th

Abstract excerpt

Myeloperoxidase (MPO) is an oxidative enzyme expressed in polymorphonuclear leukocytes. It is involved in the defence against periodontal bacteria, and is also able to mediate inflammatory tissue destruction in periodontal disease. A G/A polymorphism in the promoter region of the MPO gene at position -463 has been assumed to exert profound effects on the expression of the enzyme. It is the aim of this study to...

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Source

Identifiers

PMID: 11960308
DOI: 10.1038/sj.gene.6363840

Genes

MPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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