Article
Inactivation of a Helicobacter pylori DNA methyltransferase alters dnaK operon expression following host-cell adherence.
FEMS microbiology letters - 5 Mar 2002
Donahue John P, Israel Dawn A, Torres Victor J, Necheva Antoaneta S, Miller Geraldine G
Abstract excerpt
The Helicobacter pylori hpyIM gene encodes a type II DNA methyltransferase that is highly conserved among strains. To investigate the potential role of M.HpyI methyltransferase activity in controlling gene expression in H. pylori, we analyzed gene transcription profiles in wild-type strain J166 and an isogenic hpyIM mutant strain using gene arrays. This analysis showed that the expression of a majority of genes...
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