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Article

CTNNB1 mutations and beta-catenin expression in endometrial carcinomas.

Human pathology - 1 Feb 2002

Machin Pilar, Catasus Lluis, Pons Cristina, Muñoz Josefina, Matias-Guiu Xavier, Prat Jaime

Abstract excerpt

Mutations in the beta-catenin gene (CTNNB 1) with abnormal nuclear accumulation of beta-catenin have recently been identified in endometrial carcinoma (EC). Their relationship with microsatellite instability (MI) is unclear. It has been suggested that matrix metalloproteinase-7 (MMP-7) and cyclin D1 (cD) genes are targets for beta-catenin activation. DNA from 73 patients with EC was obtained from tumor and normal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11957146
DOI: 10.1053/hupa.2002.30723

Genes

CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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