Article
Abnormalities of E- and P-cadherin and catenin (beta-, gamma-catenin, and p120ctn) expression in endometrial cancer and endometrial atypical hyperplasia.
The Journal of pathology - 1 Apr 2003
Moreno-Bueno Gema, Hardisson David, Sarrió David, Sánchez Carolina, Cassia Raúl, Prat Jaime, Herman James G, Esteller Manel, Matías-Guiu Xavier, Palacios José
Abstract excerpt
Abnormal expression of cadherins and catenins plays a critical role in the initiation and progression of multiple human tumours. This study aimed to evaluate the immunoreactivity of E- and P-cadherin, beta- and gamma-catenin, and p120ctn in premalignant and malignant endometrial lesions and to correlate their membranous expression with clinicopathological features. In addition, we examined whether or not LOH and...
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