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Hypoexpression and Epigenetic Regulation of Candidate Tumor Suppressor Gene <i>CADM-2</i> in Human Prostate Cancer

10 Nov 2010

Abstract excerpt

PURPOSE: Cell adhesion molecules (CADM) comprise a newly identified protein family whose functions include cell polarity maintenance and tumor suppression. CADM-1, CADM-3, and CADM-4 have been shown to act as tumor suppressor genes in multiple cancers including prostate cancer. However, CADM-2 expression has not been determined in prostate cancer. EXPERIMENTAL DESIGN: The CADM-2 gene was cloned and characterized...

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PMID: 21062931
DOI: 10.1158/1078-0432.ccr-10-1461

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