Article
Characterization of the invasive and metastatic phenotype in human renal cell carcinoma.
Clinical & experimental metastasis - 1 Jan 2000
Saiki I, Naito S, Yoneda J, Azuma I, Price J E, Fidler I J
Abstract excerpt
The purpose of these studies was to identify some characteristics of metastatic cells and deficiencies of non-metastatic cells in the heterogeneous SN12 human renal cell carcinoma. The SN12 parental line and several isolated variants with different metastatic potential were studied both in vivo and in vitro. We compared the ability of metastatic and non-metastatic cells to adhere to components of the...
Topics
- Adult
- Animals
- Carcinoma, Renal Cell
- Cell Adhesion
- Cell Aggregation
- Collagen
- Endopeptidases
- Extracellular Matrix
- Female
- Humans
- Idoxuridine
- Iodine Radioisotopes
