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Article

Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity.

Endocrinology - 1 May 2002

Tomlinson Elizabeth, Fu Ling, John Linu, Hultgren Bruce, Huang Xiaojian, Renz Mark, Stephan Jean Philippe, Tsai Saio Ping, Powell-Braxton Lyn, French Dorothy, Stewart Timothy A

Abstract excerpt

The fibroblast growth factors (FGFs), and the corresponding receptors, are implicated in more than just the regulation of epithelial cell proliferation and differentiation. Specifically, FGF23 is a regulator of serum inorganic phosphate levels, and mice deficient in FGF receptor-4 have altered cholesterol metabolism. The recently described FGF19 is unusual in that it is nonmitogenic and appears to interact only...

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Source

Identifiers

PMID: 11956156
DOI: 10.1210/endo.143.5.8850

Genes

FGF19
FGF23

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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