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Article

Reduced PTEN expression in gastric cancer and in the gastric mucosa of gastric cancer relatives.

European journal of gastroenterology & hepatology - 1 Mar 2002

Fei Guo, Ebert Matthias P A, Mawrin Christian, Leodolter Andreas, Schmidt Norbert, Dietzmann Knut, Malfertheiner Peter

Abstract excerpt

OBJECTIVES: Gastric cancer is a leading cause of cancer-related deaths worldwide, and the genetic and molecular alterations underlying its pathogenesis are largely unknown. PTEN, a tyrosine phosphatase, is frequently mutated in brain and breast cancers but not in gastric cancers. In order to assess the role of PTEN in gastric carcinogenesis, we analysed the expression of PTEN in human gastric cancer and in the...

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Source

Identifiers

PMID: 11953696
DOI: 10.1097/00042737-200203000-00015

Genes

PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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