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Article

PTEN deletion is rare but often homogeneous in gastric cancer.

Journal of clinical pathology - 1 Aug 2012

Mina Sormeh, Bohn Benjamin A, Simon Ronald, Krohn Antje, Reeh Matthias, Arnold Dirk, Bokemeyer Carsten, Sauter Guido, Izbicki Jakob R, Marx Andreas, Stahl Phillip R

Abstract excerpt

BACKGROUND AND AIM: Gastric carcinoma is the second most frequent cause of cancer-related death worldwide. As PTEN is a potential modifier of tumour response to trastuzumab, a recently approved therapy in metastatic HER2 positive gastric cancer, the existence of PTEN deletions in primary gastric cancer was investigated. METHODS: 230 primary gastric cancers were analysed in a tissue microarray format by dual...

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PMID: 22639407
DOI: 10.1136/jclinpath-2011-200525

Genes

PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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