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Article

PTEN mutation spectrum in breast cancers and breast hyperplasia.

Journal of cancer research and clinical oncology - 1 Sept 2010

Yang Julun, Ren Yan, Wang Li, Li Baolin, Chen Yue, Zhao Wenxing, Xu Wenmang, Li Tao, Dai Fang

Abstract excerpt

PURPOSE: Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is one of the most frequently mutated human tumor suppressor genes. The present study aims to investigate the role of PTEN mutation in breast carcinogenesis by analyzing PTEN mutation spectrum and the protein expression in breast cancers, adjacent hyperplastic lesions, benign breast lesions and normal breast tissues. METHODS: All 9 exons of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20300775
DOI: 10.1007/s00432-010-0781-3

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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